research and clinical trials
Strathfield Retina Clinic has a strong commitment to clinical research and actively supports new and innovative treatments for retinal diseases. Our dedicated research unit is currently involved in a number of international clinical trials and programs involving patients with Age-Related Macular Degeneration, Diabetic Macular Oedema and Retinal Vein Occlusions. These studies are pivotal in quantifying the outcomes of current management and support the potential for future treatments.
The practice has a wide-range of experience in clinical trials and recognise the importance of research to promote understanding of eye disorders, investigate new therapeutic agents and advise patients on the best available treatment options.
Some patients enrolled in trials have the benefit of accessing new and advanced treatments during the final stages of development, prior to market release.
current clinical trials:
A phase III study of the efficacy and safety of Aflibercept 8 mg in Macular Oedema secondary to Retinal Vein Occlusion
QUASAR
RECRUITING
A phase III study of Tinlarebant to explore safety and efficacy in the treatment of geographic atrophy (GA)
PHOENIX
RECRUITING
A phase IIb study of intravitreal gene therapy treatment of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)
PARASOL
RECRUITING
Treat & Extend versus Fixed dosing with Faricimab for management of Diabetic Macular Oedema (DMO)
INSITE
RECRUITING
Assessing the efficacy and durability of intravitreal Faricimab in patients currently treated for neovascular age-related macular degeneration (nAMD)
FURGGHORN
RECRUITING
A non-interventional study to describe the patient demographics, baseline characteristics and outcomes of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD)
GALTOS
RECRUITMENT CLOSED
otx-tki
recruitment closed
A Phase I Open-Label, Single-Dose Study of OTX-TKI (axitinib implant) for Intravitreal Use in Subjects with Neovascular Age-Related Macular Degeneration (nAMD)
A Phase III, randomized, single-masked, multicenter study assessing the efficacy and safety of brolucizumab 6 mg compared to panretinal photocoagulation laser in patients with Proliferative Diabetic Retinopathy
condor
recruitment closed
A multicenter, open-label extension study to evaluate the long-term safety and tolerability of faricimab in patients with diabetic macular oedema
rhone-x
recruitMENT CLOSED
ripple-1
recruitMENT CLOSED
A Phase II evaluation of safety and efficacy of IBE-814 Intravitreal (IVT) Implant in patients with Diabetic Macular Oedema and Macular Oedema due to Retinal Vein Occlusion
A phase III, randomized, double-masked, active comparator-controlled study to evaluate the efficacy and safety of faricimab in patients with macular edema secondary to branch retinal vein occlusion (BRVO)
BALATON
RECRUitment closed
A phase III, randomized, double-masked, active comparator-controlled study to evaluate the efficacy and safety of faricimab in patients with macular edema secondary to central retinal or hemiretinal vein occlusion (CRVO)
Comino
RECRUITment closed
A phase III, multicentre, double-masked, randomised study to evaluate the efficacy and safety of Intravitreal OPT-302 in combination with Aflibercept, compared with Aflibercept alone, in participants with neovascular age-related macular degeneration (nAMD)
cOAST
RECRUITMENT CLOSED
A phase III, open-label, multicenter, Oaks extension study to evaluate the long-term safety and efficacy of Pegcetacoplan in subjects with geographic atrophy (GA) secondary to age-related macular degeneration (AMD)
GALE
RECRUITment closed
A phase II, double-masked, placebo-controlled, dose range finding study of Danicopan in patients with Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD)